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describe in this paper the creation and operation of the Open Science Grid (OSG [1]), a distributed shared cyberinfrastructure driven by the milestones of a diverse group of research communities. The effort is fundamentally collaborative, with domain scientists, computer scientists and technology specialists and providers from more than 70 U.S. universities, national laboratories and organizations providing resources, tools and expertise. The evolving OSG facility provides computing and storage resources for particle and nuclear physics, gravitational wave experiments, digital astronomy, molecular genomics, nanoscience and applied mathematics.
